Save the profile and switch to it by clicking the X52 icon in tray and selecting the name of the profile you've just created.
You might also want to clear the assignments for the scroll wheel and mouse fire the same way you did with the wheel button. Also remove the shift button for the remaining shift state by clicking the blue icon below the mode name. If you don't use the SST for Elite Dangerous I suggest you also remove all the shift state columns save for the first one by clicking the 'x' icon next to each mode name. The button will now work normally in game To fix this problem you have to create a new profile in SST (the default profile uses this button to emulate right mouse button) by clicking the X52 icon in your tray and selecting 'profile editor', then scroll down to 'wheel button' and switch it to 'unprogrammed' by clicking the arrow to the right of button name and selecting appropriate option. Don't listen to people telling you to uninstall drivers.
